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职业迁徙
个人简介
Our research program spans a broad range of chemical biology, nucleic acid chemistry and biology, RNA biology, and epigenetics. We discovered the first RNA demethylase and characterized functions of different RNA methylation binding proteins. We uncovered transcriptional and post-transcriptional gene expression regulation pathways mediated by dynamic RNA modifications such as N6-methyladenosine (m6A). We developed enabling methods to map RNA and DNA modifications, and we are exploring functional importance of different RNA modifications in diverse biological systems. We also invent new genomic methods to accurately monitor transcription and chromatin state.
研究兴趣
论文共 1066 篇作者统计合作学者相似作者
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Nature Biotechnologypp.1-12, (2024)
Nature cell biologyno. 3 (2024): 421-437
Sai Xiao,Shoubao Ma,Baofa Sun,Wenchen Pu,Songqi Duan,Jingjing Han, Yaqun Hong,Jianying Zhang,Yong Peng,Chuan He,Ping Yi, Michael A. Caligiuri,
Science Immunologyno. 95 (2024)
RNAno. 5 (2024): 548-559
STAR PROTOCOLSno. 1 (2024): 102855-102855
Qing Dai,Chang Ye, Iryna Irkliyenko, Yiding Wang,Hui-Lung Sun,Yun Gao, Yushuai Liu,Alana Beadell, José Perea,Ajay Goel,Chuan He
Nature biotechnologypp.1-12, (2024)
Yongjie Ma,Zhe Ji,Wanxin Yang,Li Li, Liqiang Han, Yu Liu,Yuanhao Guo,Adam A. Dmytriw,Chuan He,Guilin Li,Hongqi Zhang
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D-Core
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